The agreement signed by the Ministry of Science and Technology (MCT) through its agency National Council for Scientific and Technological Development (CNPq) in partnership, and by FAPESP and other Brazilian state research foundations aims to create several National Institutes of Science and Technology (INCTs), spread over the country, in a multi-centric functioning way, coordinated by host institutions recognized by their research qualification in a given specialty.
O INCT NANOFARMA representa uma importante estratégia de associação de competências já consolidadas na área de Nanotecnologia aplicada à medicamentos e cosméticos de grupos de pesquisa de várias universidades do Brasil, os quais atuam no desenvolvimento de projetos ligados à obtenção de nanocarreadores para diversas moléculas com atividade biológica, visando sua aplicação em terapias onde…
The National Institutes of Science and Technology Program (INCT), which was launched in July 2008 by the Ministry of Science and Technology - CNPq, with the collaboration of FAPESP, recruited scientists to work in networks in research areas that are strategic to the sustainable development of the country. Thus, the UFSCar aggregated in networks the best research groups in chemical ecologi…
(Only some records are available in English at this moment)
INCT-DATREM aims to form a national network of research groups active in the search for innovative technologies for the evaluation of chemical, toxicological and radioactive micropollutants, as well as the search for more efficient technologies for the treatment of waste, sewage, effluents and catchment waters, contributing to the evaluation of risk, environmental preservation, human heal…
Analytical Chemistry, in the last years, has directed great efforts to the development of analytical methods for the analysis of samples and/or analytes of biological interest. The huge impact of the researches in this area provided a race towards the development of methods for the chemical analyses of substances of live organisms. With the engagement of analytical chemists in the develop…
The development and optimization of fabrication processes for (Nd, Pr)-Fe-B alloys with restricted levels of impurities within the INCT PATRIA project is supported by the Chemical Laboratory of the Center for Metallurgical and Materials Technologies (CTMM) of the Sao Paulo Institute of Technological Research (IPT), through the chemical analysis of specimens produced, as well as the raw ma…
(Only some records are available in English at this moment)
Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder that affects approximately 1% of the population over 60 years of age and is characterized by the progressive occurrence of motor and non-motor symptoms, which end up causing difficulties in people's mobility and carrying out daily activities. The main objective of the study is to develop assistive technology …
Obesity is characterized by chronic low-grade inflammation that increases the release of inflammatory mediators, impairing insulin signaling and potentially triggering insulin resistance (IR). Due to the inability to produce insulin in the pancreas or the inefficiency in effective insulin use to control hyperglycemia, IR can progress to Type 2 Diabetes Mellitus (DMT2). The prevalence of o…
Plant cell walls are an important renewable raw material for the sustainable generation of fuels, materials and chemicals. The recalcitrance of the complex network of polysaccharides and lignin that make up the lignocellulosic component of plant cell walls makes it difficult to deconstruct the biomass by hydrolytic enzymes. Detailed knowledge of cell wall architecture can provide a ration…
(Only some records are available in English at this moment)
O projeto a ser desenvolvido pela bolsista TT-5 está relacionado às ações que estão sendo desenvolvidas no âmbito do Projeto Temático INCT - Nanotecnologia Farmacêutica (Proc. n. 2014/50928-2), bem como plano apresentado quando da solicitação da bolsa. Os tópicos envolvidos estão relacionados à microfluídica e sua aplicação na nanotecnologia e atuará em 3 vertentes: a obtenção (síntese de…
Neste projeto, serão seguidos experimentos físico-químicos da enzima lisina-cetoglutarato redutase (LKR/SDH), em estudos paralelos usando proteínas recombinantes, células humanas e extratos de plantas. A via da sacaropina é a principal via para o catabolismo da lisina em eucariotos, com conservação em plantas e animais. Nesta via, a lisina é convertida em a-aminoadipato por três reações e…
A broca-da-cana-de-açúcar, Diatraea saccharalis (Fabricius, 1794) (Lepidoptera: Crambidae), é uma das principais pragas da cana-de-açúcar, causando perdas significativas na produção e qualidade da cultura, impactando negativamente a indústria sucroenergética brasileira. Apesar de seis décadas de pesquisa sobre o feromônio sexual de D. saccharalis, sua eficácia em campo ainda não foi compr…
(Only some records are available in English at this moment)
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