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Virulence Genes and Antimicrobial Resistance Profiles of Pasteurella multocida Strains Isolated from Rabbits in Brazil

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Autor(es):

Porfida Ferreira, Thais Sebastiana1; Felizardo, Maria Roberta1; Sena de Gobbi, Debora Dirani1; Gomes, Cleise Ribeiro1; de Lima Nogueira Filsner, Pedro Henrique1; Moreno, Marina1; Paixao, Renata1; Pereira, Jucelia de Jesus1; Moreno, Andrea Micke1

Afiliação do(s) autor(es):

1Univ Sao Paulo. Fac Med Vet & Zootecnia

Tipo de documento: Artigo Científico
Fonte: THE SCIENTIFIC WORLD JOURNAL; 2012.
Citações Web of Science: 1
Resumo
Pasteurella multocida is responsible for a wide range of diseases in domestic animals. In rabbits, the agent is related to nasal discharge, pneumonia, otitis media, pyometra, orchitis, abscess, and septicemia. One hundred and forty rabbits with respiratory diseases from four rabbitries in Sao Paulo State, Brazil were evaluated for the detection of P. multocida in their nasal cavities. A total of twenty-nine animals were positive to P. multocida isolation, and 46 strains were selected and characterized by means of biochemical tests and PCR. P. multocida strains were tested for capsular type, virulence genes, and resistance profile. A total of 45.6% (21/46) of isolates belonged to capsular type A, and 54.34% (25/46) of the isolates were untypeable. None of the strains harboured toxA or pfhA genes. The frequency of the other twenty genes tested was variable, and the data generated was used to build a dendrogram, showing the relatedness of strains, which were clustered according to origin. Resistance revealed to be more common against sulfonamides and cotrimoxazole, followed by erythromycin, penicillin, and amoxicillin. (AU)

Processo FAPESP: 07/08592-3 - Isolamento e caracterização de Pasteurella multocida provenientes de cães e gatos
Beneficiário:Thaís Sebastiana Porfida Ferreira
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 07/03024-7 - Avaliação do perfil sorológico e de eliminação de Pasteurella multocida em rebanhos suínos
Beneficiário:Andrea Micke Moreno
Linha de fomento: Auxílio à Pesquisa - Regular
CDi/FAPESP - Centro de Documentação e Informação da Fundação de Amparo à Pesquisa do Estado de São Paulo

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