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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Mitochondrial Quality Control in Cardiac Diseases

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Author(s):
Campos, Juliane C. ; Bozi, Luiz H. M. ; Bechara, Luiz R. G. ; Lima, Vanessa M. ; Ferreira, Julio C. B.
Total Authors: 5
Document type: Review article
Source: FRONTIERS IN PHYSIOLOGY; v. 7, OCT 21 2016.
Web of Science Citations: 7
Abstract

Disruption of mitochondrial homeostasis is a hallmark of cardiac diseases. Therefore, maintenance of mitochondrial integrity through different surveillance mechanisms is critical for cardiomyocyte survival. In this review, we discuss the most recent findings on the central role of mitochondrial quality control processes including regulation of mitochondrial redox balance, aldehyde metabolism, proteostasis, dynamics, and clearance in cardiac diseases, highlighting their potential as therapeutic targets. (AU)

FAPESP's process: 12/14416-1 - Protein quality control profile in skeletal muscle wasting: role of BETA2- adrenergic receptor
Grantee:Juliane Cruz Campos
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 12/19379-7 - Role of ALDH2*2 mutation in heart failure: therapeutic potential of Alda-1
Grantee:Vanessa Morais Lima
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 12/05765-2 - Contribution of aldehyde dehydrogenase 2 to heart failure development
Grantee:Julio Cesar Batista Ferreira
Support type: Research Grants - Young Investigators Grants
FAPESP's process: 15/20783-5 - Protein quality control in dysfunctional/atrophic skeletal muscle: role of b2-adrenoceptor
Grantee:Julio Cesar Batista Ferreira
Support type: Regular Research Grants
FAPESP's process: 16/01633-5 - Beta2-adrenoceptor activation counteracts skeletal muscle WEAKNESS/WASTING: role of autophagy
Grantee:Juliane Cruz Campos
Support type: Scholarships abroad - Research Internship - Doctorate