CV Lattes
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Universidade de São Paulo (USP). Instituto de Física de São Carlos (IFSC) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Química from Universidade Federal do Rio de Janeiro (1954) and ph.d. at Chemistry from Universidade de São Paulo (1963). Has experience in Physic, focusing on Liquids and Solids Structure; crystallography, acting on the following subjects: estrutura cristalina, difração de raios-x, método de rietveld, estrutura molecular and cristalografia de raios-x. (Source: Lattes Curriculum)
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Our activities along the time of existence of this project will take place in two main areas: a) directly at the school in contact with teachers and students and b) through the Portal Ciência Web (www.cienciaweb.com.br). Thre overall objective of the proj (AU)
The subject of this project is the synthesis, phenomenological studies, and computational simulation of physical properties and experimental characterization of ferroelectric materials, due to their high technological importance. Although there are reported innumerous theoretical and experimental works, the study of ferroelectric materials remain as an actual subject for researches. Since…
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The objective of this activity plan is the structural characterization of copper(II) complexes with hydrazides, in order to evaluate the structural and physicochemical properties demonstrated by complexes of bioinorganic relevance. To this end, new copper(II) coordination compounds will be synthesized using ligands of the hydrazide class, which will be characterized by the techniques of s…
This activity plan aims to develop new solid forms of active pharmaceutical ingredients (APIs) in the antihypertensive class, seeking to improve the physicochemical properties demonstrated by these APIs, such as solubility, permeability and hygroscopicity. In this way, new solid forms of some drugs will be used, such as hydralazine and furosemide, which will be characterized using single-…
Pilocarpine is an alkaloid isolated from the leaves of Pilocarpus microphyllus (Rutaceae), a native plant from Brazil, known as jaborandi, which presents muscarinic agonist activity, and it is used as a miotic agent in the treatment of glaucoma. The alkaloid imidazole Epiisopiloturina (EPI) comprises 70% of purifying residue, with activity against Schistosma mansoni, and other compounds o…
Epiisopiloturine is an imidazole alkaloid extracted from Pilocarpus microphyllus Stapf ex Wardleworth, a Brazilian native plant, whose in vivo activity against Schistosoma mansoni led to parasite burden, to reduction in hepatosplenomegaly, the egg burden in faeces, and fell granuloma diameter. Epiisopilosine, another secondary metabolite from jaborandi, was tested in vitro (just accepted …
| 17 / 7 | Completed research grants |
| 26 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 45 / 12 | All research grants and scholarships |
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