CV Lattes
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Pontifícia Universidade Católica de São Paulo (PUC-SP). Faculdade de Ciências Médicas e da Saúde (FCMS) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelors degree in Biological Sciences (Licentiate) from the Federal University of São Carlos UFSCar (2014). PhD in Sciences from the Graduate Program in Evolutionary Genetics and Molecular Biology (PPGGEv/UFSCar, 2019), with a concentration in Biochemistry and Molecular Biology, conducting research at the Laboratory of Biochemistry and Biotechnology of Bioluminescent Systems (UFSCar Sorocaba). During the PhD, she carried out a research internship (BEPE/FAPESP) at the National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.Currently a postdoctoral fellow at the Biomaterials Laboratory (PUC-Sorocaba) with a FAPESP fellowship, having completed a research internship (BEPE/FAPESP, 20232024) at the Laboratory of Precision Biochemistry in Aging and Related Pathologies, Department of Biomedical and Neuromotor Sciences, University of Bologna (Italy). She is currently acting as a volunteer substitute professor in the Biochemistry discipline of the Bachelors degree in Biological Sciences at UFSCar Sorocaba Campus.She has experience in Biochemistry, Molecular Biology, and Bioluminescence applied to mammalian cells, as well as in Education, with emphasis on the theoretical analysis of science and biology textbooks, and on the development and implementation of practical Biochemistry classes for undergraduate students. (Source: Lattes Curriculum)
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The bioluminescent reporter genes that encode luciferases are among the most sensitive and frequently used to monitor non-invasively cellular processes, in real time. Unlike fluorescent reporter genes such as GFP, which have disadvantages such as autoabsorption of irradiated light, autofluorescence and phototoxicity, bioluminescent reporter genes have the advantage of producing their own …
Luciferases are enzymes responsible for bioluminescence. These enzymes catalyze the exergonic highly oxidation of substrates known as luciferins, that the energy is released as light with high efficiency. The firefly luciferase are the most known and used in the biotechnology field as ATP bioindicators reagents, biosensors, cell biomarkers, reporter genes, among other applications. In the…
The firefly luciferin-luciferase system has been used in an enormous variety of bioanalytical applications. Firefly luciferase genes have been widely used as reporters in gene expression studies and for cell tracking in biological and pathological processes, including cell proliferation studies, cytotoxicity assays, and metastasis in model animals, emerging as a novel technology replacing…
Beetle luciferases are responsible for the production of different bioluminescence colors from green to red using the same firefly D-luciferin. Some luciferin analogues such as 6´amino-analogues can extend the range of bioluminescence colors. Among several beetle luciferases that have cloned and been studied, Phrixothrix hirtus (PxRE) railroadworm luciferase is still the only one that nat…
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