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94,506 result(s)
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SmaA 7- Environmental monitoring system aquatic

Grant number:15/08601-9
Support type:Research Grants - Innovative Research in Small Business - PIPE
Duration: December 01, 2015 - August 31, 2016
Field of knowledge:Physical Sciences and Mathematics - Oceanography
Principal Investigator:Luis Carlos Pasquale Rosa
Grantee:
Company:Seip 7 Indústria e Comércio de Máquinas Ltda. - ME
Co-Principal Investigators:

Nilson Cristino da Cruz

Assoc. researchers:

Cleyton Fernandes Ferrarini ; Diego Mariano de Oliveira

Abstract

The Brazil with the discovery of pre-salt and the development of its operation, is developing new technologies to enable their operation .Our proposal is to develop a system (SMAA 7) that is not part of the production structures and is located independent of them. The purpose is to monitor, detect and mitigate leaks in subsea production plant and be an innovative system to detect oil leaks in new oil production structures of the pre-salt (where most of the production process will be under the sea, It is operated remotely) being installed close to the production plants. The main benefit is to be an independent system (not connected) in production structures and traceability of the leaks make the most efficient, fast and accurate answers to combat leakage facilitating mitigation of environmental damage. Reduction in insurance policy costs, losses (financial, image and environmental) in case of leakage, image positioning company concerned with environmental safety and monitoring of the new pre-salt production structures. The system will consist of an embedded system consists of several sensors installed. An embedded system microcontroller will be inert awaiting responses from the sensors installed on the board. Initially the first sensor check the variation in density of the liquid, enabling the operation of the main system. Once started, the microcontroller will do a second check by a light sensor, whose purpose is to check the turbidity of the liquid. The number of sensors used is designed to ensure the veracity of the leak, because maintaining a system like this is costly, and the containment of a possible leak demand a great drive by the responsible company. Once identified the leak as real will be given the alarm. If the sensor array indicates that the initial measurement does not represent a real threat, an internal algorithm the microcontroller will recalculate the default values of the sensors (its normal and alarm conditions, scan time, etc.) and based on the newly acquired data as well as the historical data, will again leave the sleeper system, awaiting a new alarm can leak. If in case of leakage of Frade field in Chevron 11/2011 where there was a crack in the field soil was detected the next day, if the system is in operation could be detected at the time of the leak, making the field was turned off immediately preventing had been a leak of 3,700 barrels of oil into the sea decreasing environmental and financial losses such as fines of up to R $ 35 million of the ANP, and R $ 95 million to compensate for environmental damage and not well operation In addition, the client will have greater support and associated image with respect to environmental safety. (AU)

Abstract

Successful drug development requires a disease target that plays a vital role in the causation and/or progression of the disease phenotype and that can be modulated with a drug molecule. In other words, therapeutically relevant targets are both “disease-modifying” and “druggable”. It has been estimated that around 10% of the entire human genome is involved in disease onset or progression, resulting in approximately 3000 potential targets suitable for therapeutic intervention. Thus, the rapid and reliable identification of the most promising targets for drug discovery efforts would be the major challenge for the pharmaceutical industry. Moreover, the knowledge of the mechanisms that govern the inflammatory process and cell survival, generated by basic research, is essential for the identification and validation of potential and more specific molecular target. Natural products are a rich source of biologically active compounds. Many of today’s medicines are either obtained directly from a natural source or were developed from a lead compound originally obtained from a natural source. Venoms and toxins from animals, plants, snakes, spiders, scorpions, insects, slugs, and microorganisms are extremely potent because the often have very specific interactions with a macromolecular target in the body. As a result, they have proved to be important not only as lead compounds in the development of novel drugs, but also as tools in studying receptors, ion channels, and enzymes. In our research group, interesting bioactive molecules from animal venoms and secretions, such as proteins (wild or recombinant form) and derived-peptides, targeting the homeostatic system and inflammatory events, have been exploited and are in different phases of development. We have been focusing our efforts on understanding their mechanism of action through the exploitation of specific signaling pathways in order to identify and validate novel molecular targets. Among the proteins’ families taken into account are lipocalins, hemolins, serine protease inhibitors, phospholipases and chaperones. In this regard, the main idea is to consider the expertise of the Butantan Institute researchers already have in computer-aided molecular design/bioinformatics/OMICS (transcriptome, proteome) field, molecular and cellular biology and immunology approaches (in vitro assays), and in vivo models and image techniques in order to create a Center of Excellence for Research in Target Discovery. (AU)

Research and development to produce conductive Masterbatches for polymer manufacturing industry

Grant number:14/22785-2
Support type:Research Grants - Innovative Research in Small Business - PIPE
Duration: November 01, 2015 - October 31, 2017
Field of knowledge:Engineering - Materials and Metallurgical Engineering
Principal Investigator:Silmara das Neves
Grantee:
Company:IQX Inove Qualyx Tecnologia e Desenvolvimento em Resinas Ltda
Abstract

This proposal aims to develop and manufacture pilot scale, conductive masterbatches to meet the market for thermoplastic resins for the manufacture of electrostatic charge dissipation (ESD products). The major challenge of this proposal is to obtain conductive masterbatch from the use of polyaniline, ie without the use of carbon black. Underscores the importance of generating products with equal or better performance and low cost compared to already marketed. Through studies and market analysis as well as query the databases of the National Intellectual Property Institute verified the need and opportunity for investment in research and development for transformation of masterbatches and compounds for new products with higher added value. Although the production processes of polymeric materials are known and dominated in industrial scale for a long time the desired innovation is the possibility of making them antistatic, conductive or dissipative from the addition of conductive masterbatch, providing ESD protection property of the product end permanently increasing the level of security provided during use. The conductive masterbatch IQX also offer the possibility of differential staining, which does not exist today in the market because the product contains ESD protection available conductive black smoke, thus presenting necessarily black. The sectors will be directly benefited, mainly: Electronic, Automotive, Textile, Chemical, Petrochemical, Pharmaceutical, among others. Two strategies are used to overcome the technical and scientific challenges of this proposal: one related to the field of process variables in thermoplastic extrusion from the introduction of different concentrations of polyaniline and other, more complex, consisting of the doping of polyaniline during the extrusion process, to improve the dispersion and, therefore, homogeneity of the obtained masterbatch. Both approaches provide for the investigation of the effect of varying the dopant of process variables, the polymer matrix, among other parameters. From the definition of the best strategy for production of conductive masterbatches, the team will focus on training for pilot scale production and placing on the market. In order to ensure the development of masters with high commercial value, both in terms of price as property, IQX seek to arouse the interest of companies already working in the industry for development work in partnership. The IQX was incorporated in 2011 and is incubated in the Development Company of High Technology Pole of Campinas - CIATEC. Was covered with a PIPE FAPESP Aid at the time of its foundation. Provides the necessary infrastructure for development and pilot scale production (up to 100 kg / day) of conductive resins and additives. The business model of the company envisages a significant increase in the revenue stream from the sale of conductive masterbatches for processors of thermoplastic and an important contribution to innovation in the industry. (AU)

Brasil Research Centre for Gas Innovation

Grant number:14/50279-4
Support type:Research Grants - Research Partnership for Technological Innovation - PITE
Duration: December 01, 2015 - November 30, 2020
Field of knowledge:Engineering - Mechanical Engineering
Cooperation agreement:BG E&P
Principal Investigator:Julio Romano Meneghini
Grantee:
Home Institution: Escola Politécnica (EP). Universidade de São Paulo (USP). São Paulo, SP, Brazil
Partner company:Universidade de São Paulo (USP). Instituto de Energia e Ambiente (IEE)
Co-Principal Investigators:

Edmilson Moutinho dos Santos ; Emílio Carlos Nelli Silva ; Reinaldo Giudici

Abstract

The FAPESP - BG BRASIL RESEARCH CENTRE FOR GAS INNOVATION (FAPESP-BG/CEPID) aims to build up a new world class Centre for Advanced Natural Gas Studies, which will focus on the sustainable uses of natural gas in the coming years. The Centre complements Fapesp's experiences in supporting high-level scientific research and technology development in energy fields. It aims to establish a world class Research Centre focused in Natural Gas investigations, innovation and dissemination of knowledge. In this venture the Natural Gas challenges are dealt with according to three distinct, but complementary, research programmes: Engineering, Physical and Chemistry and Energy Policies and Economics. The Centre brings together a technical and scientific team that has been involved, along the past years with Energy and Natural Gas problems and proposed partial solutions in conjunction with one of the cited programmes. It is the intention of the Centre to integrate this effort, exploring the distinct focuses complementarily; to give answers and provide solutions innovatively, accordingly to the better possible form, to the matters raised by the concrete engineering and economical policies problems associated to natural gas. The State of Sao Paulo's and BG global competitiveness is the main goal of USP's proposal for the FAPESP-BG/CEPID (AU)

Multi functional machine for popsicle production

Grant number:15/15793-1
Support type:Research Grants - Innovative Research in Small Business - PIPE
Duration: December 01, 2016 - November 30, 2018
Field of knowledge:Engineering - Mechanical Engineering
Principal Investigator:Marino Arpino
Grantee:
Company:Finamac Arpifrio Engenharia e Industrialização de Equipamentos Industriais Ltda (Finamac)
Abstract

Compact and modular machine for popsicle production that is independent of other external equipment to operate, combining robotics technology with fast freezing of the final product, offering to the market a solution capable of facilitating the ascent of small producers to large scale production levels and also provide versatility of work to the major producers, at reduced costs, with more safe and hygienic processes. (AU)

Industrial and commercial development of additives IQX aimed at inclusion in global market

Grant number:15/50587-3
Support type:Research Grants - Innovative Research in Small Business - PIPE
Duration: March 01, 2017 - February 28, 2019
Field of knowledge:Physical Sciences and Mathematics - Chemistry
Cooperation agreement:FINEP - PIPE/PAPPE Subvenção
Principal Investigator:Carla Maria Nascimento Polo da Fonseca
Grantee:
Company:IQX Inove Qualyx Tecnologia e Desenvolvimento em Resinas Ltda
Abstract

The objective of this proposal is the industrial and business development of IQX additives, particularly the conductive additives ((i) IQX Conductive Additives and (ii) IQX Conductive Eco-resins) and anti-vulcanizing additives ((iii) IQX Regenera). The innovation of these products is due to use the conductive polymers as conductivity agents (i and ii) the development of a polyester polyol synthesis route where the crude glycerin, derived from biodiesel production, is used as raw material (ii) and the possibility of breaking, with high seledivity, sulphidic connections (mono, di, poly) in vulcanized reclaimed rubber process without pressurizing the reaction system and without releasing unpleasant and unhealthy odors and (iii). (AU)

Development for Industrialization and Commercialization of Savetyre® - Tire Management System - Cloud, Optimization, Intellectual Property and Scalability

Grant number:15/50633-5
Support type:Research Grants - Innovative Research in Small Business - PIPE
Duration: October 01, 2016 - September 30, 2018
Field of knowledge:Interdisciplinary
Cooperation agreement:FINEP - PIPE/PAPPE Subvenção
Principal Investigator:José Caruso Gomes
Grantee:
Company:Saveway Comércio e Representações de Softwares Ltda
Abstract

This project aims to structure the basis for Savetyre's® commercial and industrial viability, providing the required quality of products, services and skills needed to escalate the marketand compete at national and International standards. Since 2008, Saveway has been developing Savetyre® - Tire Management system, including FAPESP projects such as PIPE I and PIPE II, between 2011 and 2014. (AU)

Innovation impact in school - based oral health programs

Grant number:15/50615-7
Support type:Research Grants - Innovative Research in Small Business - PIPE
Duration: October 01, 2016 - September 30, 2018
Field of knowledge:Health Sciences - Dentistry
Cooperation agreement:FINEP - PIPE/PAPPE Subvenção
Principal Investigator:Fabiano Vieira Vilhena
Grantee:
Company:Oralls Comercial Ltda. - ME
Abstract

For such efforts will be for the product to: assess water consumption and time of the brushing group activity; evaluate the perceptions of school, teachers and public service manager in relation to the KIT, with regard to the use, organoleptic characteristics, sustainability (water, educational material), cost, and quality of life; Additional technical information regarding innovative dental gel (1100 ppm F acidic); tailor the design and marketing of the product after information collected on industrial complementation technical and product awareness activities; make sure the product with regard to ANVISA and the quality seal ABO. If the expected results are achieved the company expects to incorporate more effectively market elements and, therefore, become more robust your design, improving the chances of success. More than that, it is expected to transform the perception of consumers of a product for "brushing teeth" for a product that promotes education, health, social inclusion, and more broadly, the formation of healthy citizens. (AU)

Abstract

Technological problems, such as insufficient pre-crystallization (tempering) contribute to the loss of quality of chocolate. Another issue of importance to public health is the occurrence of Salmonella outbreaks. Both problems can result in considerable damage to chocolate processing. The aim of this project is the use of D-limonene in chocolates, seeking an innovative application with technological and microbiological purposes. From a technological point of view, this monoterpene would compose the seed crystals produced with fully hydrogenated fats (hardfats) to be applied in chocolate (seeding) to accelerate the polymorphic transition to ² crystals (more stable). By this technique, it would be possible to accelerate or make unnecessary the tempering step of chocolate. From a microbiological point of view, it is proposed to evaluate the application of D-limonene as a natural antimicrobial product since studies proved the effectiveness in the inhibition of Salmonella growth. To this end, seed crystals produced by spray cooling from cocoa butter, soy and palm kernel hardfats will be produced under predetermined conditions. Tests for applying those particles will be performed on chocolate with preset dimensions and concentration of the seeds for incorporation as nucleating agents in bittersweet chocolate. Techniques involving X-ray diffraction, microscopy will be applied to evaluate the crystallization of the seeds and chocolates analytical. Finally, tests in vitro of the anti-Salmonella capacity of D-limonene pure and applied on chocolate in the proportions to be used in the crystallization seeds will be performed. (AU)

RFID platform with passive pressure and temperature sensors for tyre identification, management and data acquisition SAVETYRE v3.0

Grant number:15/01031-2
Support type:Research Grants - Innovative Research in Small Business - PIPE
Duration: September 01, 2016 - August 31, 2018
Field of knowledge:Interdisciplinary
Principal Investigator:José Caruso Gomes
Grantee:
Company:Saveway Comércio e Representações de Softwares Ltda
Abstract

The RFID Technology is an exceptionally good platform for the development of cheap and efficient wireless sensors. It´s integration with systems and mobile devices has the potential to transform the way we collect data from the environment around us (e.g. pressure, temperature, humidity, luminosity, etc.), equipment (damages, physical shock, positioning), processes and even people (In a hospital environment for instance). In industrial, supply chain and shop floor environments, this improved and facilitated form of data collection has the potential to convey information faster and much more efficiently. This allows for informed decision-making and in turn for the employment of preventive and predictive actions based on real, up to date data. As a result, companies can optimize resource use and keep processes under tight control. In this context, this project aims to develop a new RFID based passive sensing platform in order to improve the efficiency of transportation systems through tire management. These assets are usually the third greatest cost for transportation companies, falling behind maintenance and fuel costs only (D., et al., 2014). With focus on the delivery of hardware and software developed and integrated in an innovative way, the system will allow for the wireless and automated acquisition of both calibration pressure data and internal temperature data in commercial tires, in a faster and more accurate way than the current procedures. The project is based on a product version developed with the assistance and support of FAPESP (PIPE Project - Savetyre®). This version´s RFID Tag is capable of identifying a tire throughout its entire lifespan but not of collecting information on its internal state, which is the scope of this current technology innovation project. A new business intelligence system will be developed together with the new sensing components. Said system will be responsible for the processing and presentation of data to the end user. Due to the characteristics of this new sensing system, this software will have a larger and more accurate amount of data at its disposal, in turn allowing for a more intelligent and efficient management of tires than that provided by its previous version, Savetyre® PC v2.0. As a direct result, it will be possible to reduce operational costs and resource wasting as well as the environmental impact of transportations leading to the innovative transformations of the processes of use, maintenance and management of tires by logistics operators. The innovation lies, therefore, not only in the technology itself but also in the new data collection and management processes directly supported by it. It lies in the conjoint solution of integrated identification and passive sensing for tires and in the introduction of cutting edge technology in usually low tech environments such as tire shops. In environments such as the ones of Brazilian transportation companies, where the management of tires is rather rudimentary, the potential for the relative cost reduction of tires is estimated to stabilize around the 40% mark. (AU)

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